Autism and Cancer Share Risk Genes, Pathways, and Drug Targets.

نویسندگان

  • Jacqueline N Crawley
  • Wolf-Dietrich Heyer
  • Janine M LaSalle
چکیده

Autism is a neurodevelopmental disorder, diagnosed behaviorally by social and communication deficits, repetitive behaviors, and restricted interests. Recent genome-wide exome sequencing has revealed extensive overlap in risk genes for autism and for cancer. Understanding the genetic commonalities of autism(s) and cancer(s), with a focus on mechanistic pathways, could lead to repurposed therapeutics.

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عنوان ژورنال:
  • Trends in genetics : TIG

دوره 32 3  شماره 

صفحات  -

تاریخ انتشار 2016